| Place | Player | Matches | Goals | Penalties | First match | Last match |
|---|---|---|---|---|---|---|
| 1 | Toni Kroos | 36 | 18 | 3 | 2005-09-14 | 2007-09-09 |
| 2 | Fayssal Harchaoui | 26 | 0 | 0 | 2022-09-24 | 2023-12-02 |
| 3 | Eric Emanuel da Silva Moreira | 25 | 3 | 0 | 2022-09-22 | 2023-12-02 |
| 3 | Paris Brunner | 25 | 20 | 2 | 2022-09-22 | 2023-12-02 |
| 5 | Finn Jeltsch | 24 | 0 | 0 | 2022-09-24 | 2023-12-02 |
| 6 | Sascha Bigalke | 23 | 10 | 3 | 2006-10-13 | 2007-09-09 |
| 6 | Nico Perrey | 23 | 1 | 0 | 2010-09-15 | 2011-07-10 |
| 6 | Cimo Rocker | 23 | 2 | 0 | 2010-09-17 | 2011-07-10 |
| 6 | Max Moerstedt | 23 | 10 | 0 | 2022-09-24 | 2023-12-02 |
| 6 | Noah Darvich | 23 | 7 | 1 | 2022-11-25 | 2023-12-02 |
| 6 | Robert Ramsak | 23 | 7 | 0 | 2022-09-24 | 2023-12-02 |
| 6 | Almugera Kabar | 23 | 3 | 0 | 2022-09-22 | 2023-12-02 |
| 13 | Nils Teixeira | 22 | 0 | 0 | 2006-10-13 | 2007-09-09 |
| 13 | Odisseas Vlachodimos | 22 | 0 | 0 | 2010-09-17 | 2011-07-10 |
| 13 | Emre Can | 22 | 3 | 0 | 2010-09-15 | 2011-07-10 |
| 13 | Mitchell Weiser | 22 | 4 | 0 | 2010-09-04 | 2011-07-10 |
| 13 | Alexander Staff | 22 | 15 | 1 | 2024-09-04 | 2025-11-15 |
| 13 | Elias Vali Fard | 22 | 0 | 0 | 2024-09-04 | 2025-11-15 |
| 19 | Konstantin Rausch | 21 | 0 | 0 | 2006-10-13 | 2007-09-09 |
| 19 | Florian Trinks | 21 | 6 | 0 | 2008-09-18 | 2009-11-04 |
| 19 | Lennart Thy | 21 | 11 | 0 | 2008-09-18 | 2009-11-04 |
| 19 | Samed Yesil | 21 | 19 | 0 | 2010-09-15 | 2011-07-10 |
| 19 | Levent Aycicek | 21 | 8 | 1 | 2010-09-15 | 2011-07-10 |
| 19 | Luca Netz | 21 | 5 | 0 | 2018-09-07 | 2020-02-12 |
| 25 | Patrick Funk | 20 | 5 | 0 | 2006-10-13 | 2007-09-09 |
| 25 | Kevin Wolze | 20 | 2 | 0 | 2006-10-13 | 2007-09-09 |
| 25 | Richard Sukuta-Pasu | 20 | 9 | 0 | 2007-02-17 | 2007-09-09 |
| 25 | Max Schmitt | 20 | 0 | 0 | 2022-09-26 | 2023-11-24 |
| 25 | Reinhold Yabo | 20 | 1 | 0 | 2008-09-18 | 2009-11-04 |
| 25 | Kaan Ayhan | 20 | 3 | 0 | 2010-09-15 | 2011-07-10 |
| 25 | Okan Aydin | 20 | 5 | 0 | 2010-09-15 | 2011-07-10 |
| 25 | Felix Passlack | 20 | 7 | 2 | 2014-09-10 | 2015-10-29 |
| 25 | Erdinc Karakas | 20 | 3 | 0 | 2014-09-10 | 2015-10-29 |
| 25 | Osman Turay | 20 | 0 | 0 | 2024-09-04 | 2025-11-15 |
| 35 | Dennis Dowidat | 19 | 4 | 0 | 2006-10-13 | 2007-09-09 |
| 35 | Matthias Zimmermann | 19 | 0 | 0 | 2008-09-18 | 2009-11-04 |
| 35 | Marc-Andre ter Stegen | 19 | 0 | 0 | 2008-09-18 | 2009-11-04 |
| 35 | Shkodran Mustafi | 19 | 4 | 0 | 2008-09-18 | 2009-11-04 |
| 35 | Marvin Plattenhardt | 19 | 0 | 0 | 2008-10-16 | 2009-11-04 |
| 35 | Koray Gunter | 19 | 4 | 0 | 2010-09-04 | 2011-07-10 |
| 35 | Pascal Itter | 19 | 1 | 1 | 2011-08-24 | 2012-05-16 |
| 35 | Julian Brandt | 19 | 5 | 0 | 2012-03-20 | 2013-03-31 |
| 35 | Gokhan Gul | 19 | 2 | 0 | 2014-09-10 | 2015-10-29 |
| 35 | Lars Lukas Mai | 19 | 1 | 0 | 2016-09-28 | 2017-10-22 |
| 35 | Jann-Fiete Arp | 19 | 18 | 1 | 2016-09-09 | 2017-10-22 |
| 35 | Alexander Nitzl | 19 | 0 | 0 | 2016-09-09 | 2017-10-22 |
| 35 | Charles Herrmann | 19 | 6 | 0 | 2023-01-11 | 2023-11-24 |
| 35 | Nebe Sirak Domnic | 19 | 0 | 0 | 2024-09-04 | 2025-11-15 |
| 35 | Marcello Trippel | 19 | 0 | 0 | 2024-09-04 | 2025-11-15 |
| 50 | Henning Sauerbier | 18 | 3 | 0 | 2006-10-13 | 2007-08-30 |