| Place | Player | Matches | Goals | Penalties | First match | Last match |
|---|---|---|---|---|---|---|
| 1 | Kostas Katsouranis | 22 | 0 | 0 | 2004-06-12 | 2015-03-29 |
| 2 | Vasilios Torosidis | 20 | 1 | 0 | 2008-06-10 | 2015-10-08 |
| 2 | Giorgios Karagounis | 20 | 2 | 0 | 2001-03-28 | 2014-06-29 |
| 4 | Sokratis | 17 | 2 | 0 | 2010-06-17 | 2015-10-11 |
| 5 | Theofanis Gekas | 15 | 1 | 0 | 2005-06-19 | 2014-11-14 |
| 5 | Georgios Samaras | 15 | 2 | 1 | 2008-06-10 | 2014-10-14 |
| 7 | Angelos Charisteas | 14 | 5 | 0 | 2001-03-28 | 2010-06-12 |
| 7 | Orestis Karnezis | 14 | 0 | 0 | 2014-06-14 | 2015-10-11 |
| 9 | Dimitrios Salpingidis | 13 | 3 | 1 | 2008-06-18 | 2014-10-14 |
| 10 | Antonios Nikopolidis | 12 | 0 | 0 | 2004-06-12 | 2008-06-18 |
| 10 | Angelos Basinas | 12 | 1 | 1 | 2001-03-28 | 2008-06-18 |
| 10 | Kostas Mitroglou | 12 | 1 | 0 | 2012-06-12 | 2015-10-11 |
| 10 | Jose Holebas | 12 | 0 | 0 | 2012-06-08 | 2015-10-11 |
| 10 | Andreas Samaris | 12 | 1 | 0 | 2014-06-24 | 2015-10-11 |
| 15 | Panagiotis Giorgios Kone | 11 | 1 | 0 | 2014-06-14 | 2015-10-11 |
| 15 | Ioannis Maniatis | 11 | 0 | 0 | 2012-06-08 | 2014-11-14 |
| 15 | Kostas Manolas | 11 | 0 | 0 | 2014-06-14 | 2015-09-07 |
| 18 | Georgios Seitaridis | 10 | 0 | 0 | 2004-06-12 | 2010-06-12 |
| 18 | Loukas Vyntra | 10 | 0 | 0 | 2005-06-16 | 2015-09-07 |
| 18 | Theodoros Zagorakis | 10 | 0 | 0 | 2000-09-02 | 2005-06-22 |
| 21 | Traianos Dellas | 9 | 1 | 0 | 2004-06-12 | 2008-06-18 |
| 21 | Stylianos Giannakopoulos | 9 | 0 | 0 | 2004-06-12 | 2008-06-18 |
| 23 | Panagiotis Fyssas | 8 | 0 | 0 | 2004-06-12 | 2005-06-22 |
| 23 | Tasos Mitropoulos | 8 | 0 | 0 | 1983-02-23 | 1994-07-01 |
| 23 | Zisis Vryzas | 8 | 1 | 0 | 2004-06-12 | 2005-06-22 |
| 26 | Sotirios Kyrgiakos | 7 | 0 | 0 | 2005-06-16 | 2010-06-22 |
| 26 | Alexandros Tziolis | 7 | 0 | 0 | 2008-06-18 | 2015-10-08 |
| 26 | Mihalis Kapsis | 7 | 0 | 0 | 2004-06-12 | 2005-06-22 |
| 26 | Nikos Anastopoulos | 7 | 3 | 2 | 1980-06-11 | 1988-08-31 |
| 26 | Nikolaos Karelis | 7 | 1 | 0 | 2014-10-11 | 2015-10-08 |
| 31 | Kyriakos Papadopoulos | 6 | 0 | 0 | 2012-06-08 | 2015-09-04 |
| 31 | Sotiris Ninis | 6 | 0 | 0 | 2010-06-17 | 2015-06-13 |
| 31 | Lazaros Christodoulopoulos | 6 | 0 | 0 | 2014-06-24 | 2015-06-13 |
| 31 | Vassilios Tsiartas | 6 | 0 | 0 | 2000-09-02 | 2005-06-19 |
| 31 | Savvas Kofidis | 6 | 0 | 0 | 1984-02-16 | 1994-07-01 |
| 31 | Kostas Fortounis | 6 | 0 | 0 | 2012-06-08 | 2015-10-11 |
| 37 | Panagiotis Tachtsidis | 5 | 1 | 0 | 2014-09-07 | 2015-10-11 |
| 37 | Vangelis Moras | 5 | 0 | 0 | 2010-06-22 | 2015-10-11 |
| 37 | Ioannis Amanatidis | 5 | 0 | 0 | 2005-06-16 | 2008-06-18 |
| 37 | Christos Patsatzoglou | 5 | 0 | 0 | 2000-09-02 | 2010-06-22 |
| 37 | Dimitrios Papadopoulos | 5 | 0 | 0 | 2004-06-20 | 2005-06-22 |
| 37 | Stefanos Athanasiadis | 5 | 0 | 0 | 2014-10-11 | 2015-10-08 |
| 37 | Dimitrios Saravakos | 5 | 3 | 0 | 1984-09-12 | 1994-06-21 |
| 37 | Kostas Iosifidis | 5 | 0 | 0 | 1974-11-20 | 1982-02-10 |
| 37 | Giorgios Foiros | 5 | 0 | 0 | 1974-11-20 | 1980-06-14 |
| 37 | Spyros Livathinos | 5 | 0 | 0 | 1980-04-17 | 1982-02-10 |
| 37 | Christos Terzanidis | 5 | 0 | 0 | 1974-11-20 | 1980-06-14 |
| 37 | Christos Ardizoglou | 5 | 1 | 0 | 1980-04-17 | 1984-09-12 |
| 37 | Charalambos Xanthopoulos | 5 | 0 | 0 | 1980-04-17 | 1984-02-16 |
| 37 | Ioannis Fetfatzidis | 5 | 0 | 0 | 2014-06-14 | 2015-09-07 |