| Place | Player | Matches | Goals | Penalties | First match | Last match |
|---|---|---|---|---|---|---|
| 1 | Rafael Marquez | 22 | 3 | 0 | 1999-07-25 | 2014-06-29 |
| 2 | Cuauhtemoc Blanco | 19 | 12 | 2 | 1997-12-12 | 2010-06-22 |
| 3 | Carlos Salcido | 18 | 1 | 0 | 2005-06-16 | 2014-06-29 |
| 3 | Jorge Campos | 18 | 0 | 0 | 1992-10-14 | 1999-08-04 |
| 5 | Salvador Carmona | 16 | 0 | 0 | 1997-12-12 | 2005-06-19 |
| 6 | Jared Borgetti | 13 | 5 | 0 | 2001-05-30 | 2006-06-24 |
| 7 | Jesus Arellano | 12 | 0 | 0 | 1998-06-13 | 2006-06-16 |
| 8 | Antonio Carbajal | 11 | 0 | 0 | 1950-06-24 | 1966-07-19 |
| 8 | Francisco Rodriguez | 11 | 0 | 0 | 2006-06-21 | 2014-06-29 |
| 8 | Giovani Dos Santos | 11 | 1 | 0 | 2010-06-11 | 2014-06-29 |
| 8 | Andres Guardado | 11 | 1 | 0 | 2006-06-24 | 2014-06-29 |
| 12 | Chicharito | 10 | 6 | 1 | 2010-06-11 | 2014-06-29 |
| 12 | Marcelino Bernal | 10 | 1 | 0 | 1993-12-22 | 1998-06-29 |
| 14 | Ignacio Ambriz | 9 | 0 | 0 | 1992-10-14 | 1995-01-13 |
| 14 | Jose Abundis | 9 | 3 | 0 | 1997-12-12 | 2001-06-03 |
| 14 | Hector Moreno | 9 | 0 | 0 | 2010-06-17 | 2014-06-29 |
| 17 | Enrique Borja | 8 | 2 | 0 | 1966-07-13 | 1971-09-18 |
| 17 | Raul Cardenas | 8 | 1 | 0 | 1948-08-02 | 1962-06-07 |
| 17 | Tomas Boy | 8 | 0 | 0 | 1984-08-11 | 1986-06-21 |
| 17 | Ignacio Calderon | 8 | 0 | 0 | 1966-07-13 | 1971-09-18 |
| 17 | Javier Aguirre | 8 | 0 | 0 | 1984-08-11 | 1986-06-21 |
| 22 | Luis Alves | 7 | 0 | 0 | 1993-12-22 | 1995-01-10 |
| 23 | Rafael Amador | 6 | 0 | 0 | 1984-08-11 | 1986-06-21 |
| 24 | Pablo Barrera | 5 | 0 | 0 | 2010-06-17 | 2013-06-22 |
| 24 | Paul Aguilar | 5 | 0 | 0 | 2010-06-11 | 2014-06-29 |
| 24 | Juan Carreno | 5 | 2 | 0 | 1928-05-30 | 1930-07-19 |
| 24 | Guillermo Ochoa | 5 | 0 | 0 | 2013-06-22 | 2014-06-29 |
| 28 | Oribe Peralta | 4 | 1 | 0 | 2014-06-13 | 2014-06-29 |
| 28 | Miguel Layun | 4 | 0 | 0 | 2014-06-13 | 2014-06-29 |
| 28 | Raul Jimenez | 4 | 0 | 0 | 2013-06-16 | 2014-06-17 |
| 28 | Oscar Bonfiglio | 4 | 0 | 0 | 1928-05-30 | 1930-07-19 |
| 32 | Horacio Casarin | 3 | 1 | 0 | 1950-06-24 | 1950-07-02 |
| 32 | Arturo Chaires | 3 | 0 | 0 | 1966-07-13 | 1966-07-19 |
| 32 | Javier Aquino | 3 | 0 | 0 | 2013-06-16 | 2014-06-29 |
| 32 | Jose Juan Vazquez | 3 | 0 | 0 | 2014-06-13 | 2014-06-23 |
| 32 | Gabriel Caballero | 3 | 0 | 0 | 2002-06-03 | 2002-06-13 |
| 32 | Omar Bravo | 3 | 2 | 0 | 2006-06-11 | 2006-06-21 |
| 32 | Marco Fabian | 3 | 0 | 0 | 2014-06-13 | 2014-06-23 |
| 39 | Juan Alvarado | 2 | 0 | 0 | 1971-08-18 | 1971-09-08 |
| 39 | Jose Castro | 2 | 0 | 0 | 2006-06-21 | 2006-06-24 |
| 39 | Paulo Chavez | 2 | 0 | 0 | 1997-12-12 | 1997-12-14 |
| 39 | Hector Herrera | 2 | 0 | 0 | 2013-06-19 | 2014-06-13 |
| 39 | Diego Reyes | 2 | 0 | 0 | 2013-06-22 | 2014-06-29 |
| 39 | Benito Contreras | 2 | 0 | 0 | 1928-05-30 | 1928-06-05 |
| 39 | Luis Cerrilla | 2 | 0 | 0 | 1928-05-30 | 1928-06-05 |
| 39 | Genaro Bermudez | 2 | 0 | 0 | 1971-09-08 | 1971-09-18 |
| 39 | Tomas Balcazar | 2 | 1 | 0 | 1954-06-16 | 1954-06-19 |
| 39 | Ernesto Cisneros | 2 | 0 | 0 | 1966-07-19 | 1968-12-22 |
| 39 | Ignacio Basaguren | 2 | 1 | 0 | 1970-06-07 | 1970-06-11 |
| 39 | Jaime Belmonte | 2 | 1 | 0 | 1958-06-11 | 1958-06-15 |