| Place | Player | Matches | Goals | Penalties | First match | Last match |
|---|---|---|---|---|---|---|
| 1 | Kristine Lilly | 16 | 5 | 0 | 1991-11-27 | 2010-05-22 |
| 2 | Abby Wambach | 13 | 7 | 1 | 2001-09-09 | 2015-07-01 |
| 3 | Mia Hamm | 12 | 9 | 0 | 1991-11-27 | 2004-08-23 |
| 3 | Julie Foudy | 12 | 1 | 0 | 1991-11-27 | 2004-08-23 |
| 3 | Joy Fawcett | 12 | 1 | 0 | 1991-11-27 | 2004-08-23 |
| 6 | Heather O'Reilly | 11 | 2 | 0 | 2003-01-29 | 2013-04-05 |
| 6 | Shannon Boxx | 11 | 0 | 0 | 2003-10-06 | 2013-04-05 |
| 6 | Tiffeny Milbrett | 11 | 6 | 0 | 1996-03-14 | 2003-10-06 |
| 9 | Brandi Chastain | 10 | 2 | 0 | 1996-03-14 | 2004-08-23 |
| 9 | Shannon MacMillan | 10 | 0 | 0 | 1996-03-14 | 2003-01-29 |
| 11 | Briana Scurry | 9 | 0 | 0 | 1996-03-14 | 2004-08-23 |
| 11 | Hope Solo | 9 | 0 | 0 | 2005-03-15 | 2015-07-01 |
| 11 | Heather Mitts | 9 | 0 | 0 | 2001-09-09 | 2012-10-24 |
| 11 | Carli Lloyd Hollins (Lloyd) | 9 | 2 | 1 | 2006-03-15 | 2018-03-02 |
| 11 | Cindy Parlow | 9 | 3 | 0 | 1996-03-14 | 2003-10-06 |
| 16 | Alex Morgan | 8 | 3 | 0 | 2010-05-22 | 2018-03-02 |
| 17 | Kate Sobrero | 7 | 0 | 0 | 1998-06-25 | 2003-10-06 |
| 17 | Lorrie Fair | 7 | 0 | 0 | 1998-06-25 | 2003-01-29 |
| 17 | Cat Whitehill | 7 | 0 | 0 | 2001-09-09 | 2007-01-26 |
| 17 | Carla Werden Overbeck | 7 | 1 | 0 | 1991-11-27 | 1999-07-02 |
| 21 | Megan Rapinoe | 6 | 2 | 0 | 2010-05-22 | 2018-03-02 |
| 21 | Rachel Van Hollebeke (Buehler) | 6 | 0 | 0 | 2009-10-29 | 2013-03-13 |
| 21 | Lauren Holiday (Cheney) | 6 | 1 | 0 | 2007-01-26 | 2015-07-01 |
| 21 | Tobin Heath | 6 | 1 | 0 | 2012-10-20 | 2017-03-02 |
| 21 | Amy LePeilbet | 6 | 0 | 0 | 2006-03-15 | 2012-10-24 |
| 21 | Aly Wagner | 6 | 0 | 0 | 2002-01-25 | 2006-03-15 |
| 27 | Becky Sauerbrunn | 5 | 0 | 0 | 2012-10-20 | 2017-03-02 |
| 27 | Kelley O'Hara | 5 | 1 | 0 | 2012-10-20 | 2018-03-02 |
| 27 | Amy Rodriguez | 5 | 0 | 0 | 2006-03-15 | 2012-10-20 |
| 27 | Tisha Venturini | 5 | 0 | 0 | 1996-03-14 | 1998-06-28 |
| 27 | Sydney Leroux | 5 | 0 | 0 | 2012-10-20 | 2015-07-01 |
| 27 | Christie Pearce | 5 | 0 | 0 | 1997-10-12 | 2003-01-29 |
| 27 | Kate Markgraf | 5 | 0 | 0 | 1999-07-02 | 2010-05-22 |
| 27 | Christie Rampone | 5 | 0 | 0 | 2004-08-23 | 2013-04-05 |
| 27 | Lindsay Tarpley | 5 | 0 | 0 | 2003-01-29 | 2007-01-26 |
| 36 | Lynn Williams | 4 | 2 | 0 | 2017-03-02 | 2024-08-06 |
| 36 | Michelle Akers | 4 | 1 | 0 | 1991-11-27 | 2000-07-22 |
| 36 | Alyssa Naeher | 4 | 0 | 0 | 2017-03-02 | 2024-08-06 |
| 36 | Lindsey Horan | 4 | 0 | 0 | 2017-03-02 | 2024-08-06 |
| 40 | Crystal Dunn | 3 | 0 | 0 | 2013-03-13 | 2017-03-02 |
| 40 | Emily Sonnett | 3 | 0 | 0 | 2018-03-02 | 2024-08-06 |
| 40 | Yael Averbuch | 3 | 0 | 0 | 2009-10-29 | 2013-03-13 |
| 40 | Morgan Brian | 3 | 0 | 0 | 2015-07-01 | 2018-03-02 |
| 40 | Tierna Davidson | 3 | 0 | 0 | 2018-03-02 | 2024-08-06 |
| 40 | Ali Krieger | 3 | 0 | 0 | 2010-05-22 | 2015-07-01 |
| 40 | Angela Hucles | 3 | 0 | 0 | 2003-01-29 | 2007-01-26 |
| 40 | Lori Chalupny | 3 | 0 | 0 | 2005-03-15 | 2009-10-29 |
| 40 | Debbie Keller | 3 | 0 | 0 | 1997-10-12 | 1998-06-28 |
| 49 | Julie Johnston (Ertz) | 2 | 0 | 0 | 2015-07-01 | 2018-03-02 |
| 49 | Kristie Mewis | 2 | 0 | 0 | 2013-03-13 | 2013-04-05 |