| Place | Player | Team | Goals | Penalties |
|---|---|---|---|---|
| 1. | Grafite | VfL Wolfsburg | 28 | 8 |
| 2. | Edin Dzeko | VfL Wolfsburg | 26 | 0 |
| 3. | Mario Gomez | VfB Stuttgart | 24 | 0 |
| 4. | Patrick Helmes | Bayer Leverkusen | 21 | 3 |
| 5. | Vedad Ibisevic | TSG Hoffenheim | 18 | 2 |
| 6. | Claudio Pizarro | Werder Bremen | 17 | 0 |
| 7. | Milivoje Novakovic | 1. FC Köln | 16 | 2 |
| 8. | Luca Toni | Bayern München | 14 | 0 |
| 8. | Demba Ba | TSG Hoffenheim | 14 | 0 |
| 10. | Kevin Kuranyi | FC Schalke 04 | 13 | 0 |
| 10. | Artur Wichniarek | Arminia Bielefeld | 13 | 1 |
| 12. | Stefan Kiessling | Bayer Leverkusen | 12 | 0 |
| 12. | Alexander Frei | Borussia Dortmund | 12 | 6 |
| 12. | Diego | Werder Bremen | 12 | 2 |
| 12. | Mladen Petric | Hamburger SV | 12 | 0 |
| 16. | Andrij Woronin | Hertha BSC | 11 | 0 |
| 17. | Miroslav Klose | Bayern München | 10 | 1 |
| 17. | Ivica Olic | Hamburger SV | 10 | 0 |
| 19. | Nikos Liberopoulos | Eintracht Frankfurt | 9 | 2 |
| 19. | Paolo Guerrero | Hamburger SV | 9 | 0 |
| 19. | Stanislav Sestak | VfL Bochum | 9 | 0 |
| 19. | Hugo Almeida | Werder Bremen | 9 | 0 |
| 19. | Dimitar Rangelow | Energie Cottbus | 9 | 1 |
| 19. | Franck Ribery | Bayern München | 9 | 1 |
| 19. | Jefferson Farfan | FC Schalke 04 | 9 | 2 |
| 19. | Sebastian Freis | Karlsruher SC | 9 | 0 |
| 27. | Carlos Eduardo | TSG Hoffenheim | 8 | 1 |
| 27. | Jiri Stajner | Hannover 96 | 8 | 0 |
| 27. | Sejad Salihovic | TSG Hoffenheim | 8 | 3 |
| 30. | Mikael Forssell | Hannover 96 | 7 | 3 |
| 30. | Markus Rosenberg | Werder Bremen | 7 | 0 |
| 30. | Cacau | VfB Stuttgart | 7 | 0 |
| 30. | Mohamed Zidan | Borussia Dortmund | 7 | 0 |
| 30. | Nelson Valdez | Borussia Dortmund | 7 | 0 |
| 30. | Rob Friend | Borussia Mönchengladbach | 7 | 0 |
| 30. | Sami Khedira | VfB Stuttgart | 7 | 0 |
| 30. | Marko Pantelic | Hertha BSC | 7 | 0 |
| 30. | Cicero | Hertha BSC | 7 | 1 |
| 39. | Christoph Dabrowski | VfL Bochum | 6 | 0 |
| 39. | Lukas Podolski | Bayern München | 6 | 2 |
| 39. | Neven Subotic | Borussia Dortmund | 6 | 0 |
| 39. | Heiko Westermann | FC Schalke 04 | 6 | 0 |
| 39. | Raffael | Hertha BSC | 6 | 0 |
| 39. | Chinedu Obasi | TSG Hoffenheim | 6 | 0 |
| 39. | Piotr Trochowski | Hamburger SV | 6 | 2 |
| 39. | Gojko Kacar | Hertha BSC | 6 | 0 |
| 39. | Zvjezdan Misimovic | VfL Wolfsburg | 6 | 2 |
| 48. | Tim Borowski | Bayern München | 5 | 0 |
| 48. | Bastian Schweinsteiger | Bayern München | 5 | 1 |
| 48. | Sebastian Kehl | Borussia Dortmund | 5 | 0 |