| Place | Player | Matches | Goals | Penalties | First match | Last match |
|---|---|---|---|---|---|---|
| 1 | Davie Selke | 15 | 14 | 0 | 2013-08-14 | 2014-07-31 |
| 2 | Mario Gomez | 19 | 11 | 0 | 2003-02-18 | 2004-07-18 |
| 3 | Erdal Kilicarslan | 10 | 10 | 0 | 2002-08-29 | 2003-05-23 |
| 3 | Timo Werner | 14 | 10 | 2 | 2013-05-30 | 2015-07-13 |
| 5 | Hany Mukhtar | 16 | 9 | 1 | 2013-08-14 | 2014-07-31 |
| 5 | Deniz Naki | 15 | 9 | 1 | 2007-09-07 | 2008-07-26 |
| 5 | Dženan Pejčinović | 9 | 9 | 0 | 2023-09-06 | 2024-03-26 |
| 8 | Francis Onyeka | 6 | 8 | 4 | 2025-09-06 | 2025-11-15 |
| 9 | Moritz Leitner | 8 | 7 | 2 | 2010-09-06 | 2011-06-05 |
| 9 | Kai Havertz | 8 | 7 | 3 | 2017-08-31 | 2018-03-27 |
| 9 | Keke Maximilian Topp | 11 | 7 | 1 | 2022-09-21 | 2023-03-28 |
| 9 | Philipp Hofmann | 10 | 7 | 0 | 2011-09-01 | 2012-05-30 |
| 9 | Mike Hanke | 13 | 7 | 0 | 2001-09-04 | 2002-07-28 |
| 9 | Samed Yesil | 7 | 7 | 1 | 2012-08-14 | 2013-02-06 |
| 9 | Kevin-Prince Boateng | 13 | 7 | 0 | 2005-02-23 | 2006-05-30 |
| 9 | Said El Mala | 15 | 7 | 0 | 2024-09-07 | 2025-06-23 |
| 9 | Manuel Fischer | 18 | 7 | 0 | 2006-09-05 | 2008-05-27 |
| 9 | Timo Gebhart | 14 | 7 | 3 | 2007-09-07 | 2008-07-26 |
| 19 | Philipp Ochs | 11 | 6 | 2 | 2015-09-04 | 2016-07-21 |
| 19 | Lukas Podolski | 3 | 6 | 0 | 2003-10-16 | 2003-10-20 |
| 19 | Cenk Tosun | 8 | 6 | 0 | 2009-09-05 | 2010-05-23 |
| 19 | Kevin Volland | 10 | 6 | 0 | 2010-08-18 | 2011-05-31 |
| 19 | Piotr Trochowski | 19 | 6 | 0 | 2001-11-08 | 2003-05-23 |
| 19 | Richard Sukuta-Pasu | 12 | 6 | 0 | 2008-07-14 | 2009-05-26 |
| 19 | Muhammed Damar | 8 | 6 | 3 | 2022-09-21 | 2023-03-28 |
| 19 | Max Moerstedt | 13 | 6 | 0 | 2024-09-07 | 2025-06-23 |
| 19 | Max Kruse | 17 | 6 | 0 | 2006-09-05 | 2007-07-24 |
| 28 | Sascha Bigalke | 6 | 5 | 3 | 2008-09-04 | 2009-02-11 |
| 28 | Tom Bischof | 10 | 5 | 0 | 2023-09-06 | 2024-03-26 |
| 28 | Paris Brunner | 15 | 5 | 2 | 2024-09-07 | 2025-06-23 |
| 28 | Abdenour Amachaibou | 14 | 5 | 1 | 2005-09-12 | 2006-05-30 |
| 28 | Etienne Amenyido | 7 | 5 | 0 | 2016-11-13 | 2017-07-09 |
| 28 | Niclas Fullkrug | 7 | 5 | 1 | 2011-08-23 | 2012-05-30 |
| 28 | Sebastian Tyrala | 16 | 5 | 0 | 2006-09-05 | 2007-07-24 |
| 28 | Ioannis Masmanidis | 12 | 5 | 1 | 2001-11-08 | 2002-07-28 |
| 28 | Enis Bunjaki | 8 | 5 | 1 | 2015-09-04 | 2015-11-17 |
| 28 | Manuel Wintzheimer | 8 | 5 | 0 | 2017-08-31 | 2018-03-27 |
| 28 | Shawn Parker | 13 | 5 | 0 | 2011-05-31 | 2012-05-27 |
| 28 | Chinedu Ede | 10 | 5 | 0 | 2005-09-14 | 2006-05-26 |
| 28 | Sebastian Kerk | 11 | 5 | 0 | 2012-08-14 | 2013-06-10 |
| 28 | Mustafa Kucukovic | 10 | 5 | 0 | 2004-10-21 | 2005-07-23 |
| 42 | Lucas Cueto | 11 | 4 | 0 | 2014-09-05 | 2015-07-13 |
| 42 | Anis Ben-Hatira | 8 | 4 | 2 | 2006-11-14 | 2007-07-24 |
| 42 | Marcel Risse | 11 | 4 | 1 | 2008-01-21 | 2008-07-26 |
| 42 | Dennis Schmidt | 6 | 4 | 0 | 2006-10-05 | 2007-07-18 |
| 42 | Andre Schurrle | 11 | 4 | 0 | 2008-09-04 | 2009-05-26 |
| 42 | Eugen Polanski | 14 | 4 | 1 | 2004-09-15 | 2005-07-26 |
| 42 | Mesut Ozil | 11 | 4 | 0 | 2006-09-05 | 2007-07-24 |
| 42 | Brajan Gruda | 7 | 4 | 0 | 2022-09-21 | 2022-11-29 |
| 42 | Dennis Diekmeier | 18 | 4 | 0 | 2007-09-07 | 2008-07-26 |