| Place | Player | Matches | Goals | Penalties | First match | Last match |
|---|---|---|---|---|---|---|
| 1 | Angelos Charisteas | 14 | 5 | 0 | 2001-03-28 | 2010-06-12 |
| 2 | Dimitrios Salpingidis | 13 | 3 | 1 | 2008-06-18 | 2014-10-14 |
| 2 | Dimitrios Saravakos | 5 | 3 | 0 | 1984-09-12 | 1994-06-21 |
| 2 | Nikos Anastopoulos | 7 | 3 | 2 | 1980-06-11 | 1988-08-31 |
| 5 | Sokratis | 17 | 2 | 0 | 2010-06-17 | 2015-10-11 |
| 5 | Giorgios Karagounis | 20 | 2 | 0 | 2001-03-28 | 2014-06-29 |
| 5 | Georgios Samaras | 15 | 2 | 1 | 2008-06-10 | 2014-10-14 |
| 5 | Giorgos Delikaris | 2 | 2 | 0 | 1974-11-20 | 1975-10-11 |
| 9 | Giorgos Georgiadis | 2 | 1 | 0 | 2000-09-02 | 2001-03-28 |
| 9 | Andreas Samaris | 12 | 1 | 0 | 2014-06-24 | 2015-10-11 |
| 9 | Nikos Gioutsos | 1 | 1 | 0 | 1970-11-22 | 1970-11-22 |
| 9 | Angelos Basinas | 12 | 1 | 1 | 2001-03-28 | 2008-06-18 |
| 9 | Andreas Papaemmanouil | 2 | 1 | 0 | 1960-11-20 | 1961-10-22 |
| 9 | Vasilios Torosidis | 20 | 1 | 0 | 2008-06-10 | 2015-10-08 |
| 9 | Christos Ardizoglou | 5 | 1 | 0 | 1980-04-17 | 1984-09-12 |
| 9 | Kostas Mitroglou | 12 | 1 | 0 | 2012-06-12 | 2015-10-11 |
| 9 | Kostas Eleftherakis | 2 | 1 | 0 | 1970-11-22 | 1974-11-20 |
| 9 | Nikolaos Karelis | 7 | 1 | 0 | 2014-10-11 | 2015-10-08 |
| 9 | Traianos Dellas | 9 | 1 | 0 | 2004-06-12 | 2008-06-18 |
| 9 | Panagiotis Giorgios Kone | 11 | 1 | 0 | 2014-06-14 | 2015-10-11 |
| 9 | Panagiotis Tachtsidis | 5 | 1 | 0 | 2014-09-07 | 2015-10-11 |
| 9 | Zisis Vryzas | 8 | 1 | 0 | 2004-06-12 | 2005-06-22 |
| 9 | Theofanis Gekas | 15 | 1 | 0 | 2005-06-19 | 2014-11-14 |
| 9 | Kostas Stafylidis | 4 | 1 | 0 | 2014-10-14 | 2015-10-11 |
| 9 | Christos Aravidis | 3 | 1 | 0 | 2015-09-04 | 2015-10-08 |
| 26 | Giorgios Tzavellas | 2 | 0 | 0 | 2012-06-16 | 2012-06-22 |
| 26 | Sotirios Kyrgiakos | 7 | 0 | 0 | 2005-06-16 | 2010-06-22 |
| 26 | Grigoris Makos | 2 | 0 | 0 | 2012-06-16 | 2012-06-22 |
| 26 | Michail Sifakis | 3 | 0 | 0 | 2012-06-12 | 2012-06-22 |
| 26 | Kyriakos Papadopoulos | 6 | 0 | 0 | 2012-06-08 | 2015-09-04 |
| 26 | Orestis Karnezis | 14 | 0 | 0 | 2014-06-14 | 2015-10-11 |
| 26 | Lazaros Christodoulopoulos | 6 | 0 | 0 | 2014-06-24 | 2015-06-13 |
| 26 | Panagiotis Fyssas | 8 | 0 | 0 | 2004-06-12 | 2005-06-22 |
| 26 | Sotiris Ninis | 6 | 0 | 0 | 2010-06-17 | 2015-06-13 |
| 26 | Dimitrios Papadopoulos | 5 | 0 | 0 | 2004-06-20 | 2005-06-22 |
| 26 | Adam-Kristof Tzanetpoulos | 1 | 0 | 0 | 2015-10-11 | 2015-10-11 |
| 26 | Nikos Spyropoulos | 2 | 0 | 0 | 2008-06-18 | 2010-06-22 |
| 26 | Christos Patsatzoglou | 5 | 0 | 0 | 2000-09-02 | 2010-06-22 |
| 26 | Yannis Goumas | 4 | 0 | 0 | 2000-09-02 | 2005-06-22 |
| 26 | Paraskevas Antzas | 2 | 0 | 0 | 2008-06-10 | 2008-06-18 |
| 26 | Alexandros Tzorvas | 3 | 0 | 0 | 2010-06-12 | 2010-06-22 |
| 26 | Ioannis Amanatidis | 5 | 0 | 0 | 2005-06-16 | 2008-06-18 |
| 26 | Stylianos Giannakopoulos | 9 | 0 | 0 | 2004-06-12 | 2008-06-18 |
| 26 | Vangelis Moras | 5 | 0 | 0 | 2010-06-22 | 2015-10-11 |
| 26 | Stathis Tavlaridis | 2 | 0 | 0 | 2005-06-19 | 2005-06-22 |
| 26 | Avraam Papadopoulos | 4 | 0 | 0 | 2010-06-12 | 2012-06-08 |
| 26 | Nikos Karabelas | 1 | 0 | 0 | 2014-11-14 | 2014-11-14 |
| 26 | Konstantinos Chalkias | 2 | 0 | 0 | 2012-06-08 | 2012-06-12 |
| 26 | Pantelis Kapetanos | 1 | 0 | 0 | 2010-06-12 | 2010-06-12 |
| 26 | Georgios Fotakis | 2 | 0 | 0 | 2012-06-12 | 2012-06-22 |